The Gore Calcified Vessel Project Team has been tasked with designing and manufacturing twelve vessel models intended for simulation and medical testing. These models must accurately replicate human anatomical vessels and simulate the physiological characteristics associated with a diseased state, including, blood substitute pressure, and vessel dimensions. The client, W.L. Gore & Associates, plans to use these models to evaluate the deployment of their medical devices. Therefore, it is essential for the team to ensure that the models accurately replicate human anatomy and physiological conditions.

The original project proposal from the sponsor is as follows:

"The scope of the project is to design, build, and test a replicable model of calcified lesions in the Peripheral Arterial System for the deployment of peripheral vascular interventional devices under simulated use conditions, using non-biological materials."