Project Description
Scope
The Calcified Vessel Model project team has been tasked with designing and manufacturing twelve vessel models intended for simulation and medical testing. These models must accurately replicate the anatomy of human blood vessels and the physiological symptoms of peripheral arterial disease (PAD), including blood vessel material properties and blood flow characteristics.
The client, Gore & Associates - Medical, intends to use these models to evaluate the deployment of their vascular interventional devices. Therefore, it is essential for the team to ensure that the models accurately replicate human artery anatomies and physiological conditions of PAD.
Location
Project: Northern Arizona University, Flagstaff, AZ
Client: Gore & Associates, Flagstaff, AZ
Constraints
This project must comply with all applicable OSHA and ANSI standards, as well as Gore & Associates standards for quality.
The final product should be capable of functioning safely at temperatures and pressures typically encountered within a human artery with peripheral arterial disease.
The lesion must accurately simulate calcification occurring in blood vessels, without using biological materials.
Tasks
Tasks from the project outline:
Develop, justify, and characterize the following attributes (recommended but not limited to):
Lesion durometer
Lesion adhesion strength
Lesion length
Lesion thickness
Degree of vessel occlusion
Allow visualization of device deployment
Document repeatable manufacturing processes
Concept Evaluation
Morphological Matrix
The morphological matrix the team used to determine their final design, made up of their selected design alternatives for each subsystem.
Selected for final design:
undermounted component layout
high-hardness 3D printer filament
adhesive paste/tape
right-side femoral artery
flexible TPU filament
glycerin mixture
Selected for prototyping only:
corn syrup mixture.
Schedule & Budget
Current Schedule
The manufacturing plan used by the team to organize their work and track their progress. It outlines all manufacturing tasks and their time requirements in chronological order.
Current Budget
The purchasing plan used by the team to organize their work and track their progress. It outlines all project expenses, including procurement, prototyping, and building of the final product.
Final Design
System Flow Diagram
The flow diagram of the final calcified vessel model system, created by the team.
Consists of the peristaltic pump, flow rate sensor, pressure transducers, vessel model, 1-way inlet, and fluid reservoir.
Further information on individual parts is available in Gallery.